Infrared photodissociation of non-covalent adducts of electrosprayed nucleotide ions

被引:36
作者
Little, DP [1 ]
McLafferty, FW [1 ]
机构
[1] CORNELL UNIV,BAKER LAB CHEM,ITHACA,NY 14853
基金
美国国家卫生研究院;
关键词
D O I
10.1016/1044-0305(95)00680-X
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Efficient dissociation of gaseous non-covalent adducts of multiply charged DNA anions can be effected by infrared irradiation to yield minimal dissociation of the DNA molecular ions-far less dissociation than by collisional activation. Examples include removal of adducted impurities from 100-mer DNA anions and removal of all 14 adducted molecules of 1,4-diaminobutane from M(15-) to M(17-) of a 50-mer DNA.
引用
收藏
页码:209 / 210
页数:2
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