Highly active antiretroviral therapy (HAART) and circulating markers of immune activation: Specific effect of HAART on neopterin

被引：18

作者：

Amirayan-Chevillard, N

Tissot-Dupont, H

Obadia, Y

Gallais, H

Mege, JL

Capo, C

机构：

[1] Univ Mediterranee, CNRS, UPRESA 6020, Unite Rickettsies,Fac Med, F-13385 Marseille 5, France

[2] Hop Concept, Serv Malad Infect, F-13005 Marseille, France

[3] Observ Reg Sante, F-13006 Marseille, France

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2000年 / 7卷 / 05期

关键词：

D O I：

10.1128/CDLI.7.5.832-834.2000

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The circulating levels of immune activation markers, including neopterin, tumor necrosis factor receptor type II, and interleukin-2 receptors, are increased in human immunodeficiency virus-infected patients. We show here that highly active antiretroviral therapy significantly decreased neopterin levels. This effect is reversible, since neopterin levels increased after the arrest of treatment. Their determination may be useful in the evaluation of the efficacy of antiretroviral therapy.

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收藏

页码：832 / 834

页数：3

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