Together at last: bHLH and LIM-HD regulators cooperate to specify motor neurons

被引:17
作者
Allan, DW [1 ]
Thor, S [1 ]
机构
[1] Harvard Univ, Sch Med, Dept Neurobiol, Boston, MA 02115 USA
关键词
D O I
10.1016/S0896-6273(03)00329-5
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
bHLH and LIM-HD transcription factors were originally thought to act at different stages of neurogenesis: bHLHs as neuronal "inducers" and LIM-HDs as post-mitotic subtype determinants. These distinctions are becoming blurred, and a current study by Lee and Pfaff in this issue of Neuron shows that interaction between these factors functions to synchronize neurogenesis with neuronal cell type specification.
引用
收藏
页码:675 / 677
页数:3
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