Lipoblastoma: A case with t(7;8)(q31;q13)

被引：24

作者：

Panarello, C

Rosanda, C

Morerio, C

Russo, I

Dallorso, S

Gambini, C

Ricco, AS

Storlazzi, T

Archidiacono, N

Rocchi, M

机构：

[1] Ist Giannina Gaslini, Dept Pediat Hematol Oncol, I-16147 Genoa, Italy

[2] Ist Giannina Gaslini, Dept Pathol, I-16147 Genoa, Italy

[3] Univ Bari, Inst Genet, Bari, Italy

来源：

CANCER GENETICS AND CYTOGENETICS | 1998年 / 102卷 / 01期

关键词：

D O I：

10.1016/S0165-4608(97)00272-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Lipoblastoma is a rare benign adipose tumor which, in all of the cases so far described, presents an involvement of chromosome 8 in the region 8q11-23. We hereby report the results of the second case of lipoblastoma studied by fluorescence in situ hybridization (FISH), in a 13-month-old boy. An abnormal karyotype 46,XY,t(7;8)(q31;q13) was found in 90% of the metaphases examined, in agreement with the previously reported observations. We suggest the region 8q11-23 may contain a relevant locus for lipoblastoma origin. (C) Elsevier Science Inc., 1998.

引用

页码：12 / 14

页数：3

共 14 条

[1] A PANEL OF SUBCHROMOSOMAL PAINTING LIBRARIES REPRESENTING OVER 300 REGIONS OF THE HUMAN GENOME [J].