The benefits of atomic resolution

被引:122
作者
Dauter, Z [1 ]
Lamzin, VS [1 ]
Wilson, KS [1 ]
机构
[1] DESY,EUROPEAN MOL BIOL LAB,D-22603 HAMBURG,GERMANY
关键词
D O I
10.1016/S0959-440X(97)80078-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
After a long gestation, the elucidation of the crystal structures of proteins at atomic resolution is now maturing. The use of such data for both refinement and structure solution is advancing apace. The necessary technology is generally available, in terms of data collection, computing hardware and software. The structures appearing in the literature mainly relate to demonstration projects on native proteins. The importance of these alone is already obvious. Biologically significant results, in terms of ligand complexes and prosthetic groups, are just starting to emerge. (C) Current Biology Ltd ISSN 0959-440X
引用
收藏
页码:681 / 688
页数:8
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