Protein interaction maps for model organisms

被引：102

作者：

Walhout, AJM

Vidal, M

机构：

[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 01期

关键词：

D O I：

10.1038/35048107

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Until recently. classical genetics and biochemistry were the main techniques used to investigate how organisms develop, reproduce, behave and age. But with the availability of complete genome sequences new approaches are emerging. Complete sets of proteins 'proteomes' - can be predicted from genome sequences and used to characterize protein functions globally. For example. through the large-scale identification of physical protein-protein interactions, comprehensive protein interaction maps are being generated. And these maps might help us to understand the processes that control the biology of living organisms.

引用

页码：55 / 62

页数：8

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