An association study between polymorphisms in three genes of 14-3-3 (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein) family and paranoid schizophrenia in northern Chinese population

被引：40

作者：

Jia, YB

Yu, X

Zhang, BY

Yuan, YB

Xu, Q

Shen, YC

Shen, Y

机构：

[1] CAMS & PUMC, Inst Basic Med Sci, Natl Lab Med Mol Biol, Beijing 100005, Peoples R China

[2] Natl Ctr Human Genome Res, Beijing 100176, Peoples R China

[3] Peking Univ, Inst Mental Hlth, Beijing 100083, Peoples R China

来源：

EUROPEAN PSYCHIATRY | 2004年 / 19卷 / 06期

基金：

国家高技术研究发展计划(863计划);

关键词：

YWHAB; YWHAG; YWHAZ; SNP;

D O I：

10.1016/j.eurpsy.2004.07.006

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

We performed an association study between three SNPs in the genes of 14-3-3 family and paranoid schizophrenia. SNP rs983583 G/A in the YWHAZ gene showed significant association with paranoid schizophrenia. Our study indicated that the YWHAZ gene was a potential susceptibility gene for paranoid schizophrenia in the population studied. (C) 2004 Elsevier SAS. All rights reserved.

引用

页码：377 / 379

页数：3

共 7 条

[1] 14-3-3 proteins in the nervous system [J].

Berg, D ;

Holzmann, C ;

Riess, O .

NATURE REVIEWS NEUROSCIENCE, 2003, 4 (09) :752-762

[2] MULTIPLE SIGNIFICANCE TESTS - THE BONFERRONI METHOD .10. [J].

BLAND, JM ;

ALTMAN, DG .

BRITISH MEDICAL JOURNAL, 1995, 310 (6973) :170-170

[3] Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21 [J].

Blouin, JL ;

Dombroski, BA ;

Nath, SK ;

Lasseter, VK ;

Wolyniec, PS ;

Nestadt, G ;

Thornquist, M ;

Ullrich, G ;

McGrath, J ;

Kasch, L ;

Lamacz, M ;

Thomas, MG ;

Gehrig, C ;

Radhakrishna, U ;

Snyder, SE ;

Balk, KG ;

Neufeld, K ;

Swartz, KL ;

DeMarchi, N ;

Papadimitriou, GN ;

Dikeos, DG ;

Stefanis, CN ;

Chakravarti, A ;

Childs, B ;

Housman, DE ;

Kazazian, HH ;

Antonarakis, SE ;

Pulver, AE .

NATURE GENETICS, 1998, 20 (01) :70-73

[4] A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q [J].

Cichon, S ;

Schumacher, J ;

Müller, DJ ;

Hürter, M ;

Windemuth, C ;

Strauch, K ;

Hemmer, S ;

Schulze, TG ;

Schmidt-Wolf, G ;

Albus, M ;

Borrmann-Hassenbach, M ;

Franzek, E ;

Lanczik, M ;

Fritze, J ;

Kreiner, R ;

Reuner, U ;

Weigelt, B ;

Minges, J ;

Lichtermann, D ;

Lerer, B ;

Kanyas, K ;

Baur, MP ;

Wienker, TF ;

Maier, W ;

Rietschel, M ;

Propping, P ;

Nöthen, MM .

HUMAN MOLECULAR GENETICS, 2001, 10 (25) :2933-2944

[5] Genome scan meta-analysis of schizophrenia and bipolar disorder, part II:: Schizophrenia [J].

Lewis, CM ;

Levinson, DF ;

Wise, LH ;

DeLisi, LE ;

Straub, RE ;

Hovatta, I ;

Williams, NM ;

Schwab, SG ;

Pulver, AE ;

Faraone, SV ;

Brzustowicz, LM ;

Kaufmann, CA ;

Garver, DL ;

Gurling, HMD ;

Lindholm, E ;

Coon, H ;

Moises, HW ;

Byerley, W ;

Shaw, SH ;

Mesen, A ;

Sherrington, R ;

O'Neill, FA ;

Walsh, D ;

Kendler, KS ;

Ekelund, J ;

Paunio, T ;

Lönnqvist, J ;

Peltonen, L ;

O'Donovan, MC ;

Owen, MJ ;

Wildenauer, DB ;

Maier, W ;

Nestadt, G ;

Blouin, JL ;

Antonarakis, SE ;

Mowry, BJ ;

Silverman, JM ;

Crowe, RR ;

Cloninger, CR ;

Tsuang, MT ;

Malaspina, D ;

Harkavy-Friedman, JM ;

Svrakic, DM ;

Bassett, AS ;

Holcomb, J ;

Kalsi, G ;

McQuillin, A ;

Brynjolfson, J ;

Sigmundsson, T ;

Petursson, H .

AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (01) :34-48

[6]

Möller HJ, 2003, J CLIN PSYCHIAT, V64, P23

[7] SCHIZOPHRENIA - DEVELOPMENTAL NEUROSCIENCE AND PATHOBIOLOGY [J].

WADDINGTON, JL .

LANCET, 1993, 341 (8844) :531-536

← 1 →