Evidence-Based Management of Patients Undergoing PCI: Contrast-Induced Acute Kidney Injury

被引:38
作者
Caixeta, Adriano
Mehran, Roxana [1 ]
机构
[1] Columbia Univ, Med Ctr, Data Coordinat & Anal Ctr Intervent Vasc Therapie, New York, NY 10022 USA
关键词
acute coronary syndrome; percutaneous coronary intervention; contrast media; PERCUTANEOUS CORONARY INTERVENTION; ACUTE-RENAL-FAILURE; INDUCED NEPHROPATHY; SODIUM-BICARBONATE; N-ACETYLCYSTEINE; CARDIAC-CATHETERIZATION; NONIONIC CONTRAST; RISK-FACTORS; LOW-OSMOLAR; PREVENTION;
D O I
10.1002/ccd.22376
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Contrast-induced acute kidney injury (CI-AKI) is one of the leading causes of hospital-acquired acute kidney injury. CI-AKI is highly prevalent in patients with well-known risk factors, including older age, chronic renal insufficiency, congestive heart failure, and diabetes. Thus far, no strategies have been shown to be effective in preventing CI-AKI beyond thorough patient selection, minimizing the amount of contrast agent, and meticulous hydration of the patient. The role of various drugs in preventing CI-AKI is still controversial and warrants future studies. Despite the remaining uncertainty regarding the degree of nephrotozicity produced by various contrast agents, nonionic low-osmolar contrast media may be preferred in patients at high risk for CI-AKI. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码:S15 / S20
页数:6
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