Genomic medicine: Alzheimer's disease and Parkinson's disease

被引：970

作者：

Nussbaum, RL ^{[1
]}

Ellis, CE ^{[1
]}

机构：

[1] NHGRI, Genet Dis Res Branch, NIH, Bethesda, MD 20892 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2003年 / 348卷 / 14期

关键词：

D O I：

10.1056/NEJM2003ra020003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1356 / 1364

页数：9

共 85 条

[1] A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe [J].

Abbas, N ;

Lücking, CB ;

Ricard, S ;

Dürr, A ;

Bonifati, V ;

De Michele, G ;

Bouley, S ;

Vaughan, JR ;

Gasser, T ;

Marconi, R ;

Broussolle, E ;

Brefel-Courbon, C ;

Harhangi, BS ;

Oostra, AB ;

Fabrizio, E ;

Böhme, GA ;

Pradier, L ;

Wood, NW ;

Filla, A ;

Meco, G ;

Denefle, P ;

Agid, Y ;

Brice, A .

HUMAN MOLECULAR GENETICS, 1999, 8 (04) :567-574

[2]

ARONSON MK, 1991, ARCH INTERN MED, V151, P989, DOI 10.1001/archinte.1991.00400050129024

[3] Set back to Alzheimer vaccine studies [J].

Birmingham, K ;

Frantz, S .

NATURE MEDICINE, 2002, 8 (03) :199-200

[4] Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism [J].

Bonifati, V ;

Rizzu, P ;

van Baren, MJ ;

Schaap, O ;

Breedveld, GJ ;

Krieger, E ;

Dekker, MCJ ;

Squitieri, F ;

Ibanez, P ;

Joosse, M ;

van Dongen, JW ;

Vanacore, N ;

van Swieten, JC ;

Brice, A ;

Meco, G ;

van Duijn, CM ;

Oostra, BA ;

Heutink, P .

SCIENCE, 2003, 299 (5604) :256-259

[5] Familial Alzheimer's disease-linked presenilin 1 variants elevate A beta 1-42/1-40 ratio in vitro and in vivo [J].

Borchelt, DR ;

Thinakaran, G ;

Eckman, CB ;

Lee, MK ;

Davenport, F ;

Ratovitsky, T ;

Prada, CM ;

Kim, G ;

Seekins, S ;

Yager, D ;

Slunt, HH ;

Wang, R ;

Seeger, M ;

Levey, AI ;

Gandy, SE ;

Copeland, NG ;

Jenkins, NA ;

Price, DL ;

Younkin, SG .

NEURON, 1996, 17 (05) :1005-1013

[6] PARKINSONS-DISEASE IN TWINS STUDIED WITH F-18 DOPA AND POSITRON EMISSION TOMOGRAPHY [J].

BURN, DJ ;

MARK, MH ;

PLAYFORD, ED ;

MARAGANORE, DM ;

ZIMMERMAN, TR ;

DUVOISIN, RC ;

HARDING, AE ;

MARSDEN, CD ;

BROOKS, DJ .

NEUROLOGY, 1992, 42 (10) :1894-1900

[7] Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum [J].

Campion, D ;

Dumanchin, C ;

Hannequin, D ;

Dubois, B ;

Belliard, S ;

Puel, M ;

Thomas-Anterion, C ;

Michon, A ;

Martin, C ;

Charbonnier, F ;

Raux, G ;

Camuzat, A ;

Penet, C ;

Mesnage, V ;

Martinez, M ;

Clerget-Darpoux, F ;

Brice, A ;

Frebourg, T .

AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 65 (03) :664-670

[8] Genes, models and Alzheimer's disease [J].

Chapman, PF ;

Falinska, AM ;

Knevett, SG ;

Ramsay, MF .

TRENDS IN GENETICS, 2001, 17 (05) :254-261

[9] Nerve inflammation halts trial for Alzheimer's drug [J].

Check, E .

NATURE, 2002, 415 (6871) :462-462

[10] β-secretase as a target for the treatment of Alzheimer's disease [J].

Citron, M .

JOURNAL OF NEUROSCIENCE RESEARCH, 2002, 70 (03) :373-379

← 1 2 3 4 5 6 7 8 9 →