The genome sequence of herpes simplex virus type 2

被引：301

作者：

Dolan, A ^{[1
]}

Jamieson, FE ^{[1
]}

Cunningham, C ^{[1
]}

Barnett, BC ^{[1
]}

McGeoch, DJ ^{[1
]}

机构：

[1] MRC, Virol Unit, Inst Virol, Glasgow G11 5JR, Lanark, Scotland

来源：

JOURNAL OF VIROLOGY | 1998年 / 72卷 / 03期

关键词：

D O I：

10.1128/JVI.72.3.2010-2021.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The genomic DNA sequence of herpes simplex virus type 2 (HSV-2) strain HG52 was determined as 154,746 bp with a G+C content of 70.4%. A total of 74 genes encoding distinct proteins was identified three of these ,were each present in two copies, within major repeat elements of the genome, The HSV-2 gene set corresponds closely with that of HSV-1, and the HSV-2 sequence prompted several local revisions to the published HSV-1 sequence (D. J. McGeoch, M. A. Dalrymple, A. J. Davison, A. Dolan, M. C. Frame, D.McNab, L. J. Perry, J. E. Scott, and P. Taylor, J. Gen. Virol. 69:1531-1574, 1988). No compelling evidence for the existence of any additional protein-coding genes in HSV-2 was identified.

引用

页码：2010 / 2021

页数：12

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