Oxidative stress status in normal ovarian cortex surrounding ovarian endometriosis

被引:108
作者
Matsuzaki, Sachiko [1 ]
Schubert, Benoit [2 ]
机构
[1] CHU Clermont Ferrand, Polyclin Hotel Dieu, F-63058 Clermont Ferrand, France
[2] Grp Hosp Pitie Salpetriere, F-75634 Paris, France
关键词
IN-VITRO FERTILIZATION; CYSTS; QUALITY; TISSUE;
D O I
10.1016/j.fertnstert.2009.08.068
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Expression levels of 8-hydroxydeoxyguanosine, a sensitive indicator of DNA damage resulting from oxidative stress, were significantly higher in samples of normal ovarian cortex surrounding endometriotic cysts when compared with ovarian cortex surrounding dermoid and serous ovarian cysts. These findings suggest that the normal ovarian cortex surrounding endometriotic tissues is more severely affected by oxidative stress than ovarian cortex adjacent to other benign ovarian cysts. (Fertil Steril (R) 2010;93:2431-2. (C) 2010 by American Society for Reproductive Medicine.)
引用
收藏
页码:2431 / 2432
页数:2
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