Glycosylated hemoglobin: Finally ready for prime time as a cardiovascular risk factor

What can we conclude from the reports by Khaw and Selvin and colleagues in this issue? First, the glycosylated hemoglobin level is an independent progressive risk factor for cardiovascular events, regardless of diabetes status. Second, glycosylated hemoglobin belongs on the list of cardiovascular risk factors. Third, these studies highlight the importance of ongoing clinical trials of reducing glycosylated hemoglobin levels to reduce cardiovascular risk.