Superiority of ratio based lymph node staging for bladder cancer

被引:255
作者
Herr, HW [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Urol, New York, NY 10021 USA
关键词
bladder; bladder neoplasms; lymph nodes; neoplasm staging; prognosis;
D O I
10.1097/01.ju.0000032474.22093.06
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: The current study evaluated lymph node staging and the outcome in patients with lymph node positive bladder cancer after radical cystectomy. Materials and Methods: A total of 162 patients with lymph node positive bladder cancer were followed a median of 7.5 years after radical cystectomy and pelvic lymph node dissection for survival and local recurrence. Lymph node disease was stratified by pN stage, the number of positive lymph nodes and the number of positive lymph nodes in relation to the number removed (ratio based pN stage). Results: A median of 13 lymph nodes (range 2 to 32) was examined, showing an average of 3.3 positive lymph nodes per specimen. An increased number of lymph nodes correlated with the identification of lymph node positive cases. The ratio of the number of positive-to-total number of lymph nodes removed better defined surgical outcome than conventional lymph node staging. Conclusions: Ratio based lymph node staging, which reflects the number of lymph nodes examined and the quality of lymph node dissection, was a significant prognostic variable for survival and local control in patients with lymph node positive bladder cancer after radical cystectomy.
引用
收藏
页码:943 / 945
页数:3
相关论文
共 8 条
[1]  
[Anonymous], 1997, AJCC CANC STAGING MA
[2]   Impact of the number of lymph nodes retrieved on outcome in patients with muscle invasive bladder cancer [J].
Herr, HW ;
Bochner, BH ;
Dalbagni, G ;
Donat, SM ;
Reuter, VE ;
Bajorin, DF .
JOURNAL OF UROLOGY, 2002, 167 (03) :1295-1298
[3]   Outcome of patients with grossly node positive bladder cancer after pelvic lymph node dissection and radical cystectomy [J].
Herr, HW ;
Donat, SM .
JOURNAL OF UROLOGY, 2001, 165 (01) :62-64
[4]  
Leissner J, 2002, J UROLOGY, V167, P264
[5]   Pelvic lymph node metastases from bladder cancer: Outcome in 83 patients after radical cystectomy and pelvic lymphadenectomy [J].
Mills, RD ;
Turner, WH ;
Fleischmann, A ;
Markwalder, R ;
Thalmann, GN ;
Studer, UE .
JOURNAL OF UROLOGY, 2001, 166 (01) :19-23
[6]   Radical cystectomy in the treatment of invasive bladder cancer: Long-term results in 1,054 patients [J].
Stein, JP ;
Lieskovsky, G ;
Cote, R ;
Groshen, S ;
Feng, AC ;
Boyd, S ;
Skinner, E ;
Bochner, B ;
Thangathurai, D ;
Mikhail, M ;
Raghavan, D ;
Skinner, DG .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (03) :666-675
[7]   Pelvic lymph node dissection can be curative in patients with node positive bladder cancer [J].
Vieweg, J ;
Gschwend, JE ;
Herr, HW ;
Fair, WR .
JOURNAL OF UROLOGY, 1999, 161 (02) :449-454
[8]   Volume of lymphatic metastases does not independently influence prognosis in colorectal cancer [J].
Wong, JH ;
Steinemann, S ;
Tom, P ;
Morita, S ;
Tauchi-Nishi, P .
JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (06) :1506-1511