Regioselective microbial oxidation of bile acids

被引:16
作者
Fantin, G [1 ]
Ferrarini, S [1 ]
Medici, A [1 ]
Pedrini, P [1 ]
Poli, S [1 ]
机构
[1] Univ Ferrara, Dipartmento Chim, I-44100 Ferrara, Italy
关键词
D O I
10.1016/S0040-4020(97)10408-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
High regioselectivity in the microbial oxidation of C-7, C-3 and C-12 hydroxyl groups of cholic, chenodeoxycholic, deoxycholic and hyocholic acids 1-4 is reported. The tested microrganisms have been isolated from 50 enviromental samples withdrawed from an industry that extracts and purify bile acids. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1937 / 1942
页数:6
相关论文
共 4 条
[1]   Biotransformations on steroid nucleus of bile acids [J].
Bortolini, O ;
Medici, A ;
Poli, S .
STEROIDS, 1997, 62 (8-9) :564-577
[2]  
IIDA T, 1989, J LIPID RES, V30, P1267
[3]  
Kritchevsky D, 1971, BILE ACIDS CHEM PHYS, V1
[4]   PREPARATIVE-SCALE REGIO-SPECIFIC AND STEREOSPECIFIC OXIDOREDUCTION OF CHOLIC-ACID AND DEHYDROCHOLIC ACID-CATALYZED BY HYDROXYSTEROID DEHYDROGENASES [J].
RIVA, S ;
BOVARA, R ;
PASTA, P ;
CARREA, G .
JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (15) :2902-2906