Psychotropic medication consumption patterns in the UK general population

被引:137
作者
Ohayon, MM
Caulet, M
Priest, RG
Guilleminault, C
机构
[1] Ctr Rech Philippe Pinel Montreal, Montreal, PQ H1C 1H1, Canada
[2] Univ London, Imperial Coll Sch Med St Marys, Acad Dept Psychiat, Paterson Ctr, London, England
[3] Stanford Univ, Sch Med, Sleep Disorders Ctr, Stanford, CA 94305 USA
关键词
antidepressant; anxiolytic; hypnotic; psychotropic; epidemiology;
D O I
10.1016/S0895-4356(97)00238-2
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
The prevalence of psychotropic medication consumption was assessed in the UK by surveying a representative sample of 4972 non-institutionalized individuals 15 years of age or older (participation rate, 79.6%). A questionnaire was administered over the telephone with the help of the Sleep-Eval Expert System. Topics covered included: type and name of medication, indication, dosage, duration of intake, and medical specialty of prescriber. Also collected were data pertaining to sociodemographics, physical illnesses, and DSM-IV mental disorders. Overall, 3.5% [95% CI: 3-4] of the sample reported current use of psychotropic medication. Consumption was higher among women (4.6% [3.8-5.4]) than men (2.3% [1.7-2.9]), and among the elderly (greater than or equal to 65 years of age). The distribution of psychotropics was: hypnotics 1.5%, antidepressants 1.1%, and anxiolytics 0.8%. The median duration of psychotropic intake was 52 weeks. General practitioners were the most common prescribers of psychotropics (over 80% for each class of drug). Nearly half the antidepressant: users were diagnosed by the system with a DSM-IV anxiety disorder, and one-fifth the anxiolytic users with a depressive disorder. A marked improvement in sleep quality was reported by half the subjects using a psychotropic for sleep-enhancing purposes. Psychotropic users were more likely than non-users to report episodes of memory loss, vertigo, or anemia. Psychotropic medication consumption is lower and patterns of psychotropic prescription differ in the UK compared with other European and North American countries. Results suggest that physicians may not be sufficiently trained to deal with the overlap between general practice and psychiatry. (C) 1998 Elsevier Science Inc.
引用
收藏
页码:273 / 283
页数:11
相关论文
共 30 条
[1]   REGULAR HYPNOTIC DRUG-TREATMENT IN A SAMPLE OF 32,679 SWEDES - ASSOCIATIONS WITH SOMATIC AND MENTAL-HEALTH, INPATIENT PSYCHIATRIC DIAGNOSES AND SUICIDE, DERIVED WITH AUTOMATED RECORD-LINKAGE [J].
ALLGULANDER, C ;
NASMAN, P .
PSYCHOSOMATIC MEDICINE, 1991, 53 (01) :101-108
[2]   MEASURING DEPRESSION IN THE COMMUNITY - A COMPARISON OF TELEPHONE AND PERSONAL INTERVIEWS [J].
ANESHENSEL, CS ;
FRERICHS, RR ;
CLARK, VA ;
YOKOPENIC, PA .
PUBLIC OPINION QUARTERLY, 1982, 46 (01) :110-121
[3]  
BALTER MB, 1992, J CLIN PSYCHIAT, V53, P34
[4]   WITHDRAWAL REACTION AFTER LONG-TERM THERAPEUTIC USE OF BENZODIAZEPINES [J].
BUSTO, U ;
SELLERS, EM ;
NARANJO, CA ;
CAPPELL, H ;
SANCHEZCRAIG, M ;
SYKORA, K .
NEW ENGLAND JOURNAL OF MEDICINE, 1986, 315 (14) :854-859
[5]  
*CAN PHARM ASS, 1994, COMP PHARM SPEC
[6]   PATTERNS OF BENZODIAZEPINE USE IN GREAT-BRITAIN AS MEASURED BY A GENERAL-POPULATION SURVEY [J].
DUNBAR, GC ;
PERERA, MH ;
JENNER, FA .
BRITISH JOURNAL OF PSYCHIATRY, 1989, 155 :836-841
[7]   COGNITIVE IMPAIRMENT IN LONG-TERM BENZODIAZEPINE USERS [J].
GOLOMBOK, S ;
MOODLEY, P ;
LADER, M .
PSYCHOLOGICAL MEDICINE, 1988, 18 (02) :365-374
[8]  
Hosmer D., 1989, Applied Logistic Regression, V1st, DOI DOI 10.1097/00019514-200604000-00003
[9]  
KISH L, 1965, SURVYE SAMPLING
[10]   VIGILANCE IMPAIRMENT AFTER A SINGLE-DOSE OF BENZODIAZEPINES [J].
KOZENA, L ;
FRANTIK, E ;
HORVATH, M .
PSYCHOPHARMACOLOGY, 1995, 119 (01) :39-45