Endogenous RhoA inhibitor protects endothelial barrier

被引：22

作者：

Amerongen, Geerten P. van Nieuw

van Hinsbergh, Victor W. M.

机构：

[1] Vrije Univ Amsterdam, Med Ctr, Dept Physiol, NL-1081 BT Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Med Ctr, Inst Cardiovasc Res, NL-1081 BT Amsterdam, Netherlands

来源：

CIRCULATION RESEARCH | 2007年 / 101卷 / 01期

关键词：

D O I：

10.1161/CIRCRESAHA.106.156513

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：7 / 9

页数：3

共 24 条

[1] Transient and prolonged increase in endothelial permeability induced by histamine and thrombin -: Role of protein kinases, calcium, and RhoA [J].

Amerongen, GPV ;

Draijer, R ;

Vermeer, MA ;

van Hinsbergh, VWM .

CIRCULATION RESEARCH, 1998, 83 (11) :1115-1123

[2] GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction [J].

Birukova, AA ;

Adyshev, D ;

Gorshkov, B ;

Bokoch, GM ;

Birukov, KG ;

Verin, AD .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2006, 290 (03) :L540-L548

[3] Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase [J].

Cullere, X ;

Shaw, SK ;

Andersson, L ;

Hirahashi, J ;

Luscinskas, FW ;

Mayadas, TN .

BLOOD, 2005, 105 (05) :1950-1955

[4] GDIs: central regulatory molecules in Rho GTPase activation [J].

DerMardirossian, C ;

Bokoch, GM .

TRENDS IN CELL BIOLOGY, 2005, 15 (07) :356-363

[5] Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling [J].

DerMardirossian, Celine ;

Rocklin, Gabriel ;

Seo, Ji-Yeon ;

Bokoch, Gary M. .

MOLECULAR BIOLOGY OF THE CELL, 2006, 17 (11) :4760-4768

[6] Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells [J].

Essler, M ;

Amano, M ;

Kruse, HJ ;

Kaibuchi, K ;

Weber, PC ;

Aepfelbacher, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (34) :21867-21874

[7] Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an epac-rap1 signaling pathway [J].

Fukuhara, S ;

Sakurai, A ;

Sano, H ;

Yamagishi, A ;

Somekawa, S ;

Takakura, N ;

Saito, Y ;

Kangawa, K ;

Mochizuki, N .

MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (01) :136-146

[8] RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs [J].

Gorovoy, Matvey ;

Neamu, Radu ;

Niu, Jiaxin ;

Vogel, Stephen ;

Predescu, Dan ;

Miyoshi, Jun ;

Takai, Yoshimi ;

Kini, Vidisha ;

Mehta, Dolly ;

Malik, Asrar B. ;

Voyno-Yasenetskaya, Tatyana .

CIRCULATION RESEARCH, 2007, 101 (01) :50-58

[9] Vascular pharmacology of acute lung injury and acute respiratory distress syndrome [J].

Groeneveld, ABJ .

VASCULAR PHARMACOLOGY, 2002, 39 (4-5) :247-256

[10] Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP - Role in regulation of endothelial permeability [J].

Holinstat, M ;

Knezevic, N ;

Broman, M ;

Samarel, AM ;

Malik, AB ;

Mehta, D .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (04) :2296-2305

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