Value of self-reportable screening criteria to identify asymptomatic individuals in the general population for urogential Chlamydia trachomatis infection screening

被引:9
作者
Andersen, B
van Valkengoed, I
Olesen, F
Moller, JK
Ostergaard, L
机构
[1] Aarhus Univ, Res Unit, DK-8000 Aarhus C, Denmark
[2] Aarhus Univ, Dept Gen Practice, DK-8000 Aarhus C, Denmark
[3] Aarhus Univ Hosp, Skejby Sygehus, Dept Clin Microbiol, DK-8000 Aarhus, Denmark
[4] Aarhus Univ Hosp, Skejby Sygehus, Dept Infect Dis, Res Unit Q, DK-8000 Aarhus, Denmark
[5] Univ Amsterdam, Acad Med Ctr, HIV Monitoring Fdn, NL-1105 AZ Amsterdam, Netherlands
关键词
D O I
10.1086/368188
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Submission of samples from the home allows screening for Chlamydia trachomatis without preceding professional assessment of clinical risk factors. Therefore, a validation of self-reportable information for use as selective screening criteria is needed. We asked a total of 1175 women and 1033 men who participated in an in-home sampling screening study to provide information on behavior and sociodemographic characteristics. In a multivariate model, selective screening criteria were developed on the basis of information from a random part of the tested population (development group), and the validity was assessed for the remaining part of the tested population (validation group). To find all infections, 95% of the subjects had to be screened, and screening 63% of them would have detected 86% of infections. Low predictive values were found when selective screening criteria from other studies were assessed. Selective screening by means of in-home sampling strategies among men and women aged 21-23 years cannot be recommended in the area studied.
引用
收藏
页码:837 / 844
页数:8
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