Antiplatelet activity of Varthemia iphionoides

被引：29

作者：

Afifi, FU ^{[1
]}

Aburjai, T ^{[1
]}

机构：

[1] Univ Jordan, Fac Pharm, Dept Pharmaceut Sci, Amman 11942, Jordan

来源：

FITOTERAPIA | 2004年 / 75卷 / 7-8期

关键词：

Varthemia iphionoides; xanthomicrol; kumatokenin; jaceidin; 3,3 '-di-O-methylquercetin; antiplatelet activity;

D O I：

10.1016/j.fitote.2004.04.014

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Aqueous and alcoholic extracts, volatile oil and four flavonoids, xanthomicrol (1), kumatokenin (2), jaceidin (3) and 3, 3'-di-O-methylquercetin (4), isolated from Varthemia iphionoides were investigated for their in vitro anti-platelet activity. Aqueous extract and compounds (1), (2) and (4) showed anti-platelet activity. Volatile oil and the alcoholic extract did not exhibit any anti-platelet activity. Structures of the isolated compounds (l)-(4) were determined by spectroscopic methods (UV, IR, MS, H-1-NMR). (C) 2004 Elsevier B.V All rights reserved.

引用

页码：629 / 633

页数：5

共 7 条

[1] Anti-platelet stilbenes from aerial parts of Rheum palaestinum [J].

Aburjai, TA .

PHYTOCHEMISTRY, 2000, 55 (05) :407-410

[2]

AFIFI F, 1990, Dirasat Series B Pure and Applied Sciences, V17, P176

[3] ANTIFUNGAL FLAVONOIDS FROM VARTHEMIA-IPHIONOIDES [J].

AFIFI, FU ;

ALKHALIL, S ;

ABDULHAQ, BK ;

MAHASNEH, A ;

ALEISAWI, DM ;

SHARAF, M ;

WONG, LK ;

SCHIFF, PL .

PHYTOTHERAPY RESEARCH, 1991, 5 (04) :173-175

[4]

AL-EISAWI D M, 1982, Mitteilungen der Botanischen Staatssammlung Muenchen, V18, P79

[5]

Barakat Abu-Rmailah B., 2000, Dirasat. Medical and Biological Sciences, V27, P53

[6]

BERETZ A, 1991, METHODS PLANT BIOCH, V6, P235

[7]

FEINBRUNDOTHAN N, 1977, FLORA PALAESTINA, P316

← 1 →