Plant genome modification by homologous recombination

被引:88
作者
Hanin, M
Paszkowski, J
机构
[1] Inst Super Biotechnol Sfax, Sfax, Tunisia
[2] Friedrich Miescher Inst Biomed Res, CH-4058 Basel, Switzerland
关键词
D O I
10.1016/S1369-5266(03)00016-5
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The mechanisms and frequencies of various types of homologous recombination (HR) have been studied in plants for several years. However, the application of techniques involving HR for precise genome modification is still not routine. The low frequency of HR remains the major obstacle but recent progress in gene targeting in Arabidopsis and rice, as well as accumulating knowledge on the regulation of recombination levels, is an encouraging sign of the further development of HR-based approaches for genome engineering in plants.
引用
收藏
页码:157 / 162
页数:6
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