Antigen specificity of T-cell response to Mycobacterium avium infection in mice

被引：20

作者：

Pais, TF ^{[1
]}

Cunha, JF ^{[1
]}

Appelberg, R ^{[1
]}

机构：

[1] Univ Porto, Inst Mol & Cell Biol, Lab Microbiol & Immunol Infect, P-4150180 Porto, Portugal

来源：

INFECTION AND IMMUNITY | 2000年 / 68卷 / 08期

关键词：

D O I：

10.1128/IAI.68.8.4805-4810.2000

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T cells from Mycobacterium avium-infected C57BL/6 mice reacted to culture filtrate, envelope, and cytosol proteins and to fractions obtained from these proteins. Multiple targets were recognized, such as 29- to 45-kDa and <21-kDa antigens of the culture Filtrate, antigens of around 30 kDa in the envelope and cytosol, and 45-to 116-kDa proteins in the envelope.

引用

页码：4805 / 4810

页数：6

共 25 条

[1] Induction of a type 1 immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae [J].

AbouZeid, C ;

Gares, MP ;

Inwald, J ;

Janssen, R ;

Zhang, Y ;

Young, DB ;

Hetzel, C ;

Lamb, JR ;

Baldwin, SL ;

Orme, IM ;

Yeremeev, V ;

Nikonenko, BV ;

Apt, AS .

INFECTION AND IMMUNITY, 1997, 65 (05) :1856-1862

[2] Host responses and antigens involved in protective immunity to Mycobacterium tuberculosis [J].

Andersen, P .

SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1997, 45 (02) :115-131

[3] EFFECTIVE VACCINATION OF MICE AGAINST MYCOBACTERIUM-TUBERCULOSIS INFECTION WITH A SOLUBLE MIXTURE OF SECRETED MYCOBACTERIAL PROTEINS [J].

ANDERSEN, P .

INFECTION AND IMMUNITY, 1994, 62 (06) :2536-2544

[4] SIMULTANEOUS ELECTROELUTION OF WHOLE SDS-POLYACRYLAMIDE GELS FOR THE DIRECT CELLULAR ANALYSIS OF COMPLEX PROTEIN MIXTURES [J].

ANDERSEN, P ;

HERON, I .

JOURNAL OF IMMUNOLOGICAL METHODS, 1993, 161 (01) :29-39

[5] Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis [J].

Baldwin, SL ;

D'Souza, C ;

Roberts, AD ;

Kelly, BP ;

Frank, AA ;

Lui, MA ;

Ulmer, JB ;

Huygen, K ;

McMurray, DM ;

Orme, IM .

INFECTION AND IMMUNITY, 1998, 66 (06) :2951-2959

[6]

BARNES PF, 1992, J IMMUNOL, V148, P1835

[7] Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis [J].

Belisle, JT ;

Vissa, VD ;

Sievert, T ;

Takayama, K ;

Brennan, PJ ;

Besra, GS .

SCIENCE, 1997, 276 (5317) :1420-1422

[8] BIOLOGICAL-ACTIVITY OF PROTEIN ANTIGENS ISOLATED FROM MYCOBACTERIUM-TUBERCULOSIS CULTURE FILTRATE [J].

COLLINS, FM ;

LAMB, JR ;

YOUNG, DB .

INFECTION AND IMMUNITY, 1988, 56 (05) :1260-1266

[9] BCG VACCINATION AGAINST TUBERCULOSIS AND LEPROSY [J].

FINE, PEM .

BRITISH MEDICAL BULLETIN, 1988, 44 (03) :691-703

[10] PEPTIDOGLYCAN-ASSOCIATED POLYPEPTIDES OF MYCOBACTERIUM-TUBERCULOSIS [J].

HIRSCHFIELD, GR ;

MCNEIL, M ;

BRENNAN, PJ .

JOURNAL OF BACTERIOLOGY, 1990, 172 (02) :1005-1013

← 1 2 3 →