Cytokinesis: The central spindle takes center stage

被引:30
作者
McCollum, D [1 ]
机构
[1] Univ Massachusetts, Sch Med, Worcester, MA 01605 USA
关键词
D O I
10.1016/j.cub.2004.10.040
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The central spindle plays a key role in cytokinesis. Recent studies have shed new light on how assembly of the central spindle is regulated, and also support a role for both the central spindle and astral microtubules in cytokinesis in animal cells.
引用
收藏
页码:R953 / R955
页数:3
相关论文
共 18 条
[1]   Determining the position of the cell division plane [J].
Canman, JC ;
Cameron, LA ;
Maddox, PS ;
Straight, A ;
Tirnauer, JS ;
Mitchison, TJ ;
Fang, GW ;
Kapoor, TM ;
Salmon, ED .
NATURE, 2003, 424 (6952) :1074-1078
[2]   Cytokinesis: progress on all fronts [J].
Glotzer, M .
CURRENT OPINION IN CELL BIOLOGY, 2003, 15 (06) :684-690
[3]   Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKIp2 [J].
Gruneberg, U ;
Neef, R ;
Honda, R ;
Nigg, EA ;
Barr, FA .
JOURNAL OF CELL BIOLOGY, 2004, 166 (02) :167-172
[4]   The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo [J].
Gruneberg, U ;
Glotzer, M ;
Gartner, A ;
Nigg, EA .
JOURNAL OF CELL BIOLOGY, 2002, 158 (05) :901-914
[5]   PRC1: A human mitotic spindle-associated CDK substrate protein required for cytokinesis [J].
Jiang, W ;
Jimenez, G ;
Wells, NJ ;
Hope, TJ ;
Wahl, GM ;
Hunter, T ;
Fukunaga, R .
MOLECULAR CELL, 1998, 2 (06) :877-885
[6]   Localization of pavarotti-KLP in living Drosophila embryos suggests roles in reorganizing the cortical cytoskeleton during the mitotic cycle [J].
Minestrini, G ;
Harley, AS ;
Glover, DM .
MOLECULAR BIOLOGY OF THE CELL, 2003, 14 (10) :4028-4038
[7]   Cell cycle regulation of central spindle assembly [J].
Mishima, M ;
Pavicic, V ;
Grüneberg, N ;
Nigg, EA ;
Glotzer, M .
NATURE, 2004, 430 (7002) :908-913
[8]   PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone [J].
Mollinari, C ;
Kleman, JP ;
Jiang, W ;
Schoehn, G ;
Hunter, T ;
Margolis, RL .
JOURNAL OF CELL BIOLOGY, 2002, 157 (07) :1175-1186
[9]   Both midzone and astral microtubules are involved in the delivery of cytokinesis signals: insights from the mobility of aurora B [J].
Murata-Hori, M ;
Wang, YL .
JOURNAL OF CELL BIOLOGY, 2002, 159 (01) :45-53
[10]   Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis [J].
Murata-Hori, M ;
Tatsuka, M ;
Wang, YL .
MOLECULAR BIOLOGY OF THE CELL, 2002, 13 (04) :1099-1108