Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion

被引：42

作者：

Byl, B

Jacobs, F

Wallemacq, P

Rossi, C

de Francquen, P

Cappello, M

Leal, T

Thys, JP

机构：

[1] Free Univ Brussels, Erasme Univ Hosp, Infect Dis Clin, B-1070 Brussels, Belgium

[2] Free Univ Brussels, Erasme Univ Hosp, Dept Thorac Surg, B-1070 Brussels, Belgium

[3] Univ Catholique Louvain, St Luc Univ Hosp, Dept Clin Chem, B-1200 Brussels, Belgium

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 06期

关键词：

D O I：

10.1128/AAC.47.6.2015-2017.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Blood and pleural exudate samples were obtained from 16 patients receiving intermittent or continuous infusions of vancomycin after lung surgery. The areas under the concentration-time curves for blood and pleural exudates were identical for both administration schedules, while continuous infusion allowed the concentrations in pleural exudates to be more sustained (mean concentration, 12 mg/liter).

引用

页码：2015 / 2017

页数：3

共 13 条

[1] Cerebrospinal fluid penetration and pharmacokinetics of vancomycin administered by continuous infusion to mechanically ventilated patients in an intensive care unit [J].