Whole body BMC in pediatric Crohn disease: Independent effects of altered growth, maturation, and body composition

被引：100

作者：

Burnham, JM

Shults, J

Semeao, E

Foster, B

Zemel, BS

Stallings, VA

Leonard, MB

机构：

[1] Univ Penn, Childrens Hosp Philadelphia, Dept Pediat, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Epidemiol & Biostat, Philadelphia, PA 19104 USA

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 12期

关键词：

Crohn disease; osteoporosis; child; DXA; body composition;

D O I：

10.1359/JBMR.040908

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Whole body BMC was assessed in 104 children and young adults with CD and 233 healthy controls. CD was associated with significant deficits in BMC and lean mass, relative to height. Adjustment for lean mass eliminated the bone deficit in CD. Steroid exposure was associated with short stature but not bone deficits relative to height.

引用

页码：1961 / 1968

页数：8

共 38 条

[1] Altered bone metabolism in inflammatory bowel disease: there is a difference between Crohn's disease and ulcerative colitis
Ardizzone, S
Bollani, S
Bettica, P
Bevilacqua, M
Molteni, P
Porro, GB
[J]. JOURNAL OF INTERNAL MEDICINE, 2000, 247 (01) : 63 - 70
[2] The effect of mechanical loading on the size and shape of bone in pre-, peri-, and postpubertal girls: A study in tennis players
Bass, SL
Saxon, L
Daly, RM
Turner, CH
Robling, AG
Seeman, E
Stuckey, S
[J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2002, 17 (12) : 2274 - 2280
[3] Musculoskeletal analyses of the forearm in young women with Turner syndrome: A study using peripheral quantitative computed tomography
Bechtold, S
Rauch, F
Noelle, V
Donhauser, S
Neu, CM
Schoenau, E
Schwarz, HP
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (12) : 5819 - 5823
[4] Bone mineral density and nutritional status in children with chronic inflammatory bowel disease
Boot, AM
Bouquet, J
Krenning, EP
Keizer-Schrama, SMPFD
[J]. GUT, 1998, 42 (02) : 188 - 194
[5] CARTER DR, 1992, J BONE MINER RES, V7, P137
[6] A randomised controlled trial of standing programme on bone mineral density in non-ambulant children with cerebral palsy
Caulton, JM
Ward, KA
Alsop, CW
Dunn, G
Adams, JE
Mughal, MZ
[J]. ARCHIVES OF DISEASE IN CHILDHOOD, 2004, 89 (02) : 131 - 135
[7] Inflammatory bowel disease and predisposition to osteopenia
Cowan, FJ
Warner, JT
Dunstan, FDJ
Evans, WD
Gregory, JW
Jenkins, HR
[J]. ARCHIVES OF DISEASE IN CHILDHOOD, 1997, 76 (04) : 325 - 329
[8] Evolution of osteopenia in inflammatory bowel disease
Dinca, M
Fries, W
Luisetto, G
Peccolo, F
Bottega, F
Leone, L
Naccarato, R
Martin, A
[J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 1999, 94 (05) : 1292 - 1297
[9] Z score prediction model for assessment of bone mineral content in pediatric diseases
Ellis, KJ
Shypailo, RJ
Hardin, DS
Perez, MD
Motil, KJ
Wong, WW
Abrams, SA
[J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 (09) : 1658 - 1664
[10] OSTEOPENIA IN MEN WITH A HISTORY OF DELAYED PUBERTY
FINKELSTEIN, JS
NEER, RM
BILLER, BMK
CRAWFORD, JD
KLIBANSKI, A
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (09) : 600 - 604

← 1 2 3 4 →