The mechanical properties of fibrin for basic scientists and clinicians

被引：299

作者：

Weisel, JW ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Dept Cell & Dev Biol, Philadelphia, PA 19104 USA

来源：

BIOPHYSICAL CHEMISTRY | 2004年 / 112卷 / 2-3期

关键词：

fibrin; visco elasticiy; polymer; mechanical properties;

D O I：

10.1016/j.bpc.2004.07.029

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this review, I set forth some basic information about the mechanical properties of fibrin clots and attempt to identify the big questions remaining. The intent is to make this topic understandable to both basic scientists who are interested in blood clotting and to hematologists or cardiologists, since I believe that this is something everyone working in these fields should know. The viscoelastic properties of fibrin are remarkable and unique among polymers. Moreover, these properties are essential to the physiology of blood clotting and are important for understanding and therefore preventing and treating thrombosis. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：267 / 276

页数：10

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