Progress in blood pressure control in autosomal dominant polycystic kidney disease

被引:26
作者
Ecder, T [1 ]
Edelstein, CL [1 ]
Fick-Brosnahan, GM [1 ]
Johnson, AM [1 ]
Duley, IT [1 ]
Gabow, PA [1 ]
Schrier, RW [1 ]
机构
[1] Univ Colorado, Hlth Sci Ctr, Dept Med, Div Renal Dis & Hypertens,Sch Med, Denver, CO 80262 USA
基金
美国国家卫生研究院;
关键词
autosomal dominant polycystic kidney disease (ADPKD); blood pressure control; education; hypertension;
D O I
10.1053/ajkd.2000.8970
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Hypertension occurs commonly in autosomal dominant polycystic kidney disease (ADPKD) and is an important factor in the progression of the disease and cardiovascular mortality. The aim of this prospective 15-year study is to report the rate of blood pressure control and the potential effect of a 10-point education program developed by our center for ADPKD patients and their physicians. The patients' blood pressure treatment was managed by their primary care physicians. Three 5-year periods were analyzed in which similar rates of hypertension in patients with ADPKD were present (63% to 68%), In the first period (1985 to 1989), the rate of blood pressure control (<140/90 mm Hg) was 38% for 216 hypertensive patients with ADPKD, From 1990 to 1994, the percentage of blood pressure control increased to 55% in 194 hypertensive patients with ADPKD (P < 0.001 versus 1985 to 1989); and the level of blood pressure control increased to 64% in 181 hypertensive patients with ADPKD during 1995 to 1999 (P < 0.001 versus 1985 to 1989), Although this percentage of blood pressure control in patients with ADPKD remains suboptimal, it compares very favorably with the 27% estimated blood pressure control in patients with essential hypertension from 1991 to 1994 in the United States. (C) 2000 by the National Kidney Foundation, Inc.
引用
收藏
页码:266 / 271
页数:6
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