Synthesis and antimicrobial activity of some new pyrazoles and thieno[2,3-c]pyrazoles

被引：18

作者：

Bakhite, EA ^{[1
]}

Geies, AA ^{[1
]}

El-Kashef, HS ^{[1
]}

机构：

[1] Assiut Univ, Fac Sci, Dept Chem, Assiut 71516, Egypt

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2000年 / 157卷

关键词：

pyrazole; thieno [2,3-c] pyrazole; oxadiazole; s-triazole; antimicrobial activity;

D O I：

10.1080/10426500008040516

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Starting with 5-chloro-1,3-diphenyl-1H-pyrazole-4-carboxaldehyde (1), both of (4-cyano-1,3-diphenyl-1H-pyrazol-5-ylthio) acethydrazide (6) and 1,3-diphenyl-1H-thieno[2,3-c] pyrazole-5-carbohydrazide (15) were synthesized. These hydrazides (6 and 15) were used as key intermediates in the synthesis of other new pyrazoles 7-12 and thieno[2,3-c]pyrazoles 16-30 respectively. Some of the prepared compounds were screened in vitro for their antibacterial and antifungal activity.

引用

页码：107 / 122

页数：16

共 20 条

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[2]

BABAQI A, 1988, HETEROCYCLES, V27, P2119

[3] SYNTHESIS AND REACTIONS OF SOME NEW 3-AMINO-2-SUBSTITUTED THIENO[2,3-B]QUINOLINES [J].