Effect of statin therapy on risk of ventricular arrhythmia among patients with coronary artery disease and an implantable cardioverter-defibrillator

被引：92

作者：

Chiu, JH ^{[1
]}

Abdelhadi, RH ^{[1
]}

Chung, MK ^{[1
]}

Gurm, HS ^{[1
]}

Marrouche, NF ^{[1
]}

Saliba, WI ^{[1
]}

Natale, A ^{[1
]}

Martin, DO ^{[1
]}

机构：

[1] Cleveland Clin Fdn, Dept Cardiovasc Med, Cleveland, OH 44195 USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2005年 / 95卷 / 04期

关键词：

D O I：

10.1016/j.amjcard.2004.10.017

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hydroxymethylglutaryl coenzyme-A reductase inhibitors, or statins, have been shown to decrease mortality rates in patients who have coronary artery disease. It has been postulated that part of the mortality benefit conferred by statins is due to a decrease in ventricular arrhythmias. We assessed the effect of statin therapy on recurrent ventricular arrhythmias in 281 patients who developed coronary artery disease after implantable cardioverter-defibrillator placement. Statin therapy was associated with a significant decrease in the risk of ventricular arrhythmia that would require implantable cardioverter-defibrillator therapy. (C) 2005 by Excerpta Medica Inc.

引用

页码：490 / 491

页数：2

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