Genetic and physical delineation of the region of the mouse deafness mutation shaker-2

被引：7

作者：

Wakabayashi, Y

Kikkawa, Y

Matsumoto, Y

Shinbo, T

Kosugi, S

Chou, D

Furuya, M

Jishage, K

Noda, T

Yonekawa, H

Kominami, R

机构：

[1] NIIGATA UNIV, SCH MED, DEPT BIOCHEM 1, NIIGATA 951, JAPAN

[2] TOKYO METROPOLITAN INST MED SCI, DEPT LAB ANIM SCI, BUNKYO KU, TOKYO 113, JAPAN

[3] JAPANESE FDN CANC RES, INST CANC, DEPT CELL BIOL, TOSHIMA KU, TOKYO 170, JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1997年 / 234卷 / 01期

关键词：

D O I：

10.1006/bbrc.1997.6595

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A total of 951 backcross progeny have been obtained from a backcross segregating for the mouse deafness mutation, shaker-2(sh-2). Linkage analysis provides a detailed genetic map in the vicinity of sh-2 which comprises 40 backcross mice identified as recombinant within a 4 cM region. This allows construction of a contig consisting of 21 BAC clones across an approximately 700-kb region of sh-2. This covers the entire nonrecombinant region of sh-2 and is therefore useful to facilitate the identification of genes in the sh-2 region. (C) 1997 Academic Press.

引用

页码：107 / 110

页数：4

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