Dandy-Walker syndrome in adult mimicking myasthenia gravis

被引：10

作者：

Cardoso, Juliana ^{[1
]}

Lange, Marcos C. ^{[1
]}

Lorenzoni, Paulo J. ^{[1
]}

Scola, Rosana H. ^{[1
]}

Werneck, Lineu C. ^{[1
]}

机构：

[1] Univ Fed Parana, Hosp Clin, Dept Internal Med, Neuromuscular Neurol Div,Serv Neurol Neuromuscula, BR-80060000 Curitiba, Parana, Brazil

来源：

ARQUIVOS DE NEURO-PSIQUIATRIA | 2007年 / 65卷 / 01期

关键词：

Dandy-Walker syndrome; hydrocephalus; myasthenia gravis; palpebral ptosis;

D O I：

10.1590/S0004-282X2007000100037

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The Dandy-Walker syndrome (DWS) is a rare posterior fossa malformation. The DWS can occur associated with other brain or systemic malformations, but ocular abnormalities in this disease are rare and clinical findings mimicking myasthenia gravis have not been described to date. We report a 23-year-old woman who presented mild limitation of the ocular movements with progressive palpebral ptosis, which changed in intensity during the day. The investigation showed negative anti-acetylcholine receptor antibody, repetitive nerve stimulation and "Tensilon test", but the brain magnetic resonance image reveals DWS with hydrocephalus associated with calosal dysgenesis. The characteristic of disease, clinical manifestations and pathologic features, specially the clinical evaluation of ocular abnormalities in suspicion of DWS, including the MG in differential diagnosis are discussed.

引用

页码：173 / 175

页数：3

共 16 条

[1]

ALMEIDA GM, 1960, ARQ NEURO-PSIQUIAT, V18, P224

[2] THE DANDY-WALKER SYNDROME OR THE SO-CALLED ATRESIA OF THE FORAMEN MAGENDIE [J].