HSC-2DPAGE and the two-dimensional gel electrophoresis database of dog heart proteins

被引：26

作者：

Dunn, MJ ^{[1
]}

Corbett, JM ^{[1
]}

Wheeler, CH ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Sch Med, Harefield Hosp,Heart Sci Ctr, Natl Heart & Lung Inst,Div Cardiothorac Surg, Harefield UB9 6JH, Middx, England

来源：

ELECTROPHORESIS | 1997年 / 18卷 / 15期

关键词：

databases; dog; heart proteins; two-dimensional polyacrylamide gel electrophoresis; World Wide Web;

D O I：

10.1002/elps.1150181514

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A two-dimensional gel electrophoresis database of dog (Canis familiaris) proteins is presented. The database contains 1212 protein spots which have been characterised in terms of their pI and M-r. This database has been integrated into the HSC-2DPAGE database which is accessible on the Internet via the World Wide Web with the uniform resource location (URL): (http://www.harefield.nthames.nhs.uk/nhli/protein/index.html). Identifications for 80 of the protein spots have been obtained by visual cross-matching with the human heart protein database in HSC-2DPAGE (42 spots), N-terminal microsequence analysis (25 spots) and peptide mass fingerprinting (20 spots). This database is being used in studies of alterations in protein expression in models of heart failure and heart disease.

引用

页码：2795 / 2802

页数：8

共 28 条

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