Investigation and initial management of ambiguous genitalia

被引：52

作者：

Ahmed, S. Faisal ^{[1
]}

Rodie, Martina ^{[1
]}

机构：

[1] Univ Glasgow, Dept Child Hlth, Royal Hosp Sick Children, Glasgow G3 8SJ, Lanark, Scotland

来源：

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM | 2010年 / 24卷 / 02期

基金：

英国医学研究理事会;

关键词：

DSD; evaluation; intersex; ANDROGEN INSENSITIVITY; INTERSEX PATIENTS; TESTOSTERONE; CLASSIFICATION; SENSITIVITY; ANOMALIES; BINDING;

D O I：

10.1016/j.beem.2009.12.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Infants rarely present with truly ambiguous genitalia and such children should be evaluated by experts who work within a multidisciplinary team that is dedicated for evaluation and management of children and adults with suspected and confirmed disorders of sex development. The paediatric endocrinologist who is a vital and often the central member of this clinical team not only needs to lead the clinical evaluation of the infant systematically but also needs to be sensitive to the needs of the infant, the parents and the rest of the team. A thorough knowledge of the underlying pathophysiology and the strengths and weaknesses of the investigative tools that are available for reaching a diagnosis is crucial. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：197 / 218

页数：22

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