Rare earth triflate catalysts in the synthesis of Vitamin E and its derivatives

被引：36

作者：

Bonrath, Werner ^{[1
]}

Dittel, Claus ^{[1
]}

Giraudi, Lisa ^{[1
]}

Netscher, Thomas ^{[1
]}

Pabst, Thomas ^{[1
]}

机构：

[1] DSM Nutr Prod, Res & Dev, CH-4002 Basel, Switzerland

来源：

CATALYSIS TODAY | 2007年 / 121卷 / 1-2期

关键词：

Vitamin E; alpha-tocopherol; antioxidant; metal triflates; rare earth metal triflates;

D O I：

10.1016/j.cattod.2006.11.022

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Vitamin E is known as the most important fat-soluble antioxidant in biological systems. The scale for commercially produced (all-rac)-alpha-tocopherol reaches over 25,000 tonnes per year. The known processes for the synthesis of a-tocopherol suffer from disadvantages like formation of by-products and waste-water problem. To overcome these drawbacks, new types of catalysts have been developed. These are rare earth metal triflates, e.g. Bi(OTf)(3), Ga(OTf)(3), Tm(OTf)(3) Or Hf(OTf)(4). This new approach to Vitamin E or derivatives thereof has several advantages, based on high yields (above 94%) and selectivities. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：65 / 70

页数：6

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