Incorporation of 2-C-methyl-D-erythritol, a putative isoprenoid precursor in the mevalonate-independent pathway, into ubiquinone and menaquinone of Escherichia coli

被引：91

作者：

Duvold, T ^{[1
]}

Cali, P ^{[1
]}

Bravo, JM ^{[1
]}

Rohmer, M ^{[1
]}

机构：

[1] UNIV STRASBOURG 1,INST LE BEL,CNRS,F-67070 STRASBOURG,FRANCE

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 35期

关键词：

D O I：

10.1016/S0040-4039(97)01392-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Incorporation of deuterium labelled 2-C-methyl-D-erythritol into isoprenoid side-chains of ubiquinone and menaquinone from Escherichia coli strongly supports the proposed intermediate role of this branched sugar derivative in the mevalonate independent pathway for isoprenoid biosynthesis via glyceraldehyde 3-phosphate and pyruvate. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：6181 / 6184

页数：4

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