Influenza Outbreaks during World Youth Day 2008 Mass Gathering

被引:44
作者
Blyth, Christopher C. [1 ]
Foo, Hong [1 ]
van Hal, Sebastiaan J. [1 ]
Hurt, Aeron C. [2 ]
Barr, Ian G. [2 ]
McPhie, Kenneth [1 ]
Armstrong, Paul K. [3 ]
Rawlinson, William D. [4 ]
Sheppeard, Vicky [5 ]
Conaty, Stephen [6 ]
Staff, Michael [7 ]
Dwyer, Dominic E. [1 ]
机构
[1] Westmead Hosp, Sydney, NSW, Australia
[2] Collaborating Ctr Influenza Reference & Res, WHO, Melbourne, Vic, Australia
[3] New S Wales Dept Hlth, Sydney, NSW, Australia
[4] Prince Wales Hosp, Sydney, NSW, Australia
[5] Sydney W Publ Hlth Unit, Parramatta, NSW, Australia
[6] Sydney SW Publ Hlth Unit, Camperdown, NSW, Australia
[7] N Sydney Cent Coast Publ Hlth Unit, Hornsby, NSW, Australia
关键词
SURVEILLANCE SCHEME; VIRUS; PILGRIMS; HAJJ;
D O I
10.3201/eid1605.091136
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Influenza outbreaks during mass gatherings have been rarely described, and detailed virologic assessment is lacking. An influenza outbreak occurred during World Youth Day in Sydney, Australia, July 2008 (WYD2008). We assessed epidemiologic data and respiratory samples collected from attendees who sought treatment for influenza-like illness at emergency clinics in Sydney during this outbreak. Isolated influenza viruses were compared with seasonal influenza viruses from the 2008 influenza season. From 100 infected attendees, numerous strains were identified: oseltamivir-resistant influenza A (H1N1) viruses, oseltamivir-sensitive influenza A (H1N1) viruses, influenza A (H3N2) viruses, and strains from both influenza B lineages (B/Florida/4/2006-like and B/Malaysia/2506/2004-like). Novel viruses were introduced, and pre-WYD2008 seasonal viruses were amplified. Viruses isolated at mass gatherings can have substantial, complex, and unpredictable effects on community influenza activity. Greater flexibility by public health authorities and hospitals is required to appropriately manage and contain these outbreaks.
引用
收藏
页码:809 / 815
页数:7
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