Single-molecule fluorescence microscopy and Raman spectroscopy studies of RNA bound carbon nanotubes

被引:18
作者
Rao, R [1 ]
Lee, J [1 ]
Lu, Q [1 ]
Keskar, G [1 ]
Freedman, KO [1 ]
Floyd, WC [1 ]
Rao, AM [1 ]
Ke, PC [1 ]
机构
[1] Clemson Univ, Dept Phys & Astron, Clemson, SC 29634 USA
关键词
D O I
10.1063/1.1813631
中图分类号
O59 [应用物理学];
学科分类号
摘要
While present studies on the integration of single-walled carbon nanotubes (SWNTs) with biomolecules have centered primarily on deoxyribonucleic acid and proteins, this report is focused on the binding of SWNTs with ribonucleic acid polymer poly(rU). We present fluorescence and spectroscopic evidences for the binding of poly(rU) molecules along the contour of isolated SWNTs which suggests that the pi-stacking may dominate the hydrophobic interaction between the poly(rU) bases and the pi-electrons of the SWNTs. (C) 2004 American Institute of Physics.
引用
收藏
页码:4228 / 4230
页数:3
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