Cryopreserved embryos in the United States and their availability for research

被引:117
作者
Hoffman, DI
Zellman, GL
Fair, CC
Mayer, JF
Zeitz, JG
Gibbons, WE
Turner, TG
机构
[1] SART, Birmingham, AL 35216 USA
[2] IVF FLORIDA Reprod Associates, Margate, FL USA
[3] RAND Corp, Santa Monica, CA USA
[4] Eastern Virginia Med Sch, Jones Inst Reprod Med, Norfolk, VA 23501 USA
[5] St Davids IVF Program, Austin, TX USA
关键词
IVF; ART; cryopreserved embryos; cryopreservation; stem cells;
D O I
10.1016/S0015-0282(03)00172-9
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To determine the number of embryos stored at assisted reproductive technology (ART) clinics in the United States and their current disposition. Design: A targeted survey instrument sent by the SART-RAND team to all medical practices providing in vitro fertilization services in the United States. Result(s): The SART-RAND team surveyed all 430 ART practices in the United States. Of these practices, 340 returned surveys for analysis. The data from these surveys were merged with data taken from the 1999 SART dataset, which contains information about practice size and success rates. Responding clinics reported a total of 396,526 embryos in storage as of April 11, 2002. The vast majority of the embryos (88.2%) were targeted for patient use. Small numbers of embryos were available for research, donation, destruction, quality assurance, or other uses. Conclusion(s): Nearly 400,000 embryos are stored in the United States, the majority of which (88.2%) are targeted for patient use. Few are available for research (2.8%), limiting possible conversion into embryonic stem cell lines. (C) 2003 by American Society for Reproductive Medicine.
引用
收藏
页码:1063 / 1069
页数:7
相关论文
共 12 条
[1]   Britain poised to extend storage of frozen embryos [J].
Boulton, A .
BRITISH MEDICAL JOURNAL, 1996, 312 (7022) :10-10
[2]  
FOSTER H, 1998, WASHINGTON U LAW Q, V76, P759
[3]  
HURST T, 1999, ASSISTED CONCEPTION, V6
[4]  
HURST T, 2000, ASSISTED CONCEPTION
[5]  
Hurst T, 2001, ASSISTED CONCEPTION
[6]  
KAHN JP, 2002, ADOPTION FROZEN EMBR
[7]   Use of human gametes obtained from anonymous donors for the production of human embryonic stem cell lines [J].
Lanzendorf, SE ;
Boyd, CA ;
Wright, DL ;
Muasher, S ;
Oehninger, S ;
Hodgen, GD .
FERTILITY AND STERILITY, 2001, 76 (01) :132-137
[8]   Impact of different clinical variables on pregnancy outcome following embryo cryopreservation [J].
Oehninger, S ;
Mayer, J ;
Muasher, S .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2000, 169 (1-2) :73-77
[9]   Cryopreservation of embryos, blastocysts, and pregnancy rates of blastocysts derived from frozen-thawed embryos and frozen-thawed blastocysts [J].
Pantos, K ;
Stefanidis, K ;
Pappas, K ;
Kokkinopoulos, P ;
Petroutsou, K ;
Kokkali, G ;
Stavrou, D ;
Tzigounis, V .
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2001, 18 (11) :579-582
[10]   Embryonic stem cell lines derived from human blastocysts [J].
Thomson, JA ;
Itskovitz-Eldor, J ;
Shapiro, SS ;
Waknitz, MA ;
Swiergiel, JJ ;
Marshall, VS ;
Jones, JM .
SCIENCE, 1998, 282 (5391) :1145-1147