Estimated early-onset group B streptococcal neonatal disease

被引：94

作者：

Luck, S ^{[1
]}

Torny, M ^{[1
]}

d'Agapeyeff, K ^{[1
]}

Pitt, A ^{[1
]}

Heath, P ^{[1
]}

Breathnach, A ^{[1
]}

Russell, AB ^{[1
]}

机构：

[1] Univ London St Georges Hosp, London, England

来源：

LANCET | 2003年 / 361卷 / 9373期

关键词：

D O I：

10.1016/S0140-6736(03)13553-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Estimates of incidence of early-onset group B streptococcal (EOGBS) infection are based on blood or cerebrospinal fluid culture-proven cases, which can be falsely negative and hence underestimate the true burden of disease. Probable EOGBS infection can be defined as colonisation by group B streptococci accompanied by features of clinical sepsis. Data collected prospectively in the UK over 1 year for neonates who required a septic screen in the first 72 h of life indicated a combined rate of definite and probable EOGBS infection of 3.6 per 1000 livebirths. This estimate Indicates a much greater disease burden in the UK than that suggested by figures of culture-proven sepsis, and lends support to the need for prevention strategies.

引用

页码：1953 / 1954

页数：2

共 5 条

[1] New PCR primers for the sensitive detection and specific identification of Group B β-hemolytic streptococci in cerebrospinal fluid [J].