The Changing Microbial Epidemiology in Cystic Fibrosis

被引：604

作者：

LiPuma, John J. ^{[1
,2
]}

机构：

[1] Univ Michigan, Sch Med, Dept Pediat & Communicable Dis, Div Pediat Infect Dis, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA

来源：

CLINICAL MICROBIOLOGY REVIEWS | 2010年 / 23卷 / 02期

基金：

美国国家卫生研究院;

关键词：

BURKHOLDERIA-CEPACIA COMPLEX; RESISTANT STAPHYLOCOCCUS-AUREUS; ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS; RESPIRATORY-TRACT INFECTIONS; ACHROMOBACTER ALCALIGENES XYLOSOXIDANS; STENOTROPHOMONAS XANTHOMONAS MALTOPHILIA; NONTUBERCULOUS MYCOBACTERIAL INFECTIONS; SCEDOSPORIUM-APIOSPERMUM INFECTION; MUCOID PSEUDOMONAS-AERUGINOSA; LENGTH-POLYMORPHISM ANALYSIS;

D O I：

10.1128/CMR.00068-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Infection of the airways remains the primary cause of morbidity and mortality in persons with cystic fibrosis (CF). This review describes salient features of the epidemiologies of microbial species that are involved in respiratory tract infection in CF. The apparently expanding spectrum of species causing infection in CF and recent changes in the incidences and prevalences of infection due to specific bacterial, fungal, and viral species are described. The challenges inherent in tracking and interpreting rates of infection in this patient population are discussed.

引用

页码：299 / +

页数：26

共 358 条

[1] ROLE OF RESPIRATORY SYNCYTIAL VIRUS IN EARLY HOSPITALIZATIONS FOR RESPIRATORY-DISTRESS OF YOUNG INFANTS WITH CYSTIC-FIBROSIS [J].