The chemistry of indoles Part 86 - A novel synthetic method of pyrrolo[2,3-b]indoles and its application to the synthesis of (+/-)-debromoflustramine B

被引：39

作者：

Somei, M ^{[1
]}

Yamada, F ^{[1
]}

Izumi, T ^{[1
]}

Nakajou, M ^{[1
]}

机构：

[1] Kanazawa Univ, Fac Pharmaceut Sci, Kanazawa, Ishikawa 920, Japan

来源：

HETEROCYCLES | 1997年 / 45卷 / 12期

关键词：

D O I：

10.3987/COM-97-7989

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Methoxy-3-(2-nitrovinyl)indole (4) functions as an electrophile and reacted with various nucleophiles regioselectively at the 2-position. Employing allyl alkoxides as nucleophiles, a novel synthetic method of pyrrolo[2,3-b]indoles has been elaborated. Utilizing the method, the synthesis of (+/-)-debromoflustramine B (10b) was achieved.

引用

页码：2327 / 2330

页数：4

共 45 条

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