Novel 2-D graphical representation of DNA sequences and their numerical characterization

被引:274
作者
Randic, M
Vracko, M
Lers, N
Plavsic, D
机构
[1] Rudjer Boskovic Inst, HR-10002 Zagreb, Croatia
[2] Natl Inst Chem, Ljubljana 1001, Slovenia
关键词
D O I
10.1016/S0009-2614(02)01784-0
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
We consider a novel 2-D graphical representation of DNA sequences preserving information on sequential adjacency of bases and allowing numerical characterization. The representation avoids loss of information accompanying alternative 2-D representations in which the curve standing for DNA overlaps and intersects itself. The method is illustrated on the coding sequence of the first exon of human beta-globin gene. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
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页码:1 / 6
页数:6
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