Alcohol, host defence and society

被引：200

作者：

Nelson, S

Kolls, JK

机构：

[1] LSU Hlth Sci Ctr, Alcohol Res Ctr, New Orleans, LA 70112 USA

[2] LSU Hlth Sci Ctr, Sect Pulm Crit Care, New Orleans, LA 70112 USA

来源：

NATURE REVIEWS IMMUNOLOGY | 2002年 / 2卷 / 03期

关键词：

D O I：

10.1038/nri744

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Impaired health caused by alcohol abuse has been known throughout recorded history. Over the past century, alcohol abuse has been clearly linked to host susceptibility to infectious disease, particularly bacterial pneumonia. Recently, both acute and chronic alcohol intake have been shown to result in specific defects in innate and adaptive immunity; these could, in principle, be subjected to specific modulation to overcome the immunosuppressive effects of the most commonly abused substance in the Western world.

引用

收藏

页码：205 / 209

页数：5

相关论文

共 60 条

[1] ALCOHOL-CONSUMPTION AND ALL-CAUSE MORTALITY - COMMENT [J].

ANDERSON, P .

ADDICTION, 1995, 90 (04) :481-484

[2] Acute ethanol intoxication suppresses lung chemokine production following infection with Streptococcus pneumoniae [J].

Boé, DM ;

Nelson, S ;

Zhang, P ;

Bagby, GJ .

JOURNAL OF INFECTIOUS DISEASES, 2001, 184 (09) :1134-1142

[3]

Boffetta P, 1990, Epidemiology, V1, P342, DOI 10.1097/00001648-199009000-00003

[4] EFFECT OF ALCOHOL AND VARIOUS DISEASES ON LEUKOCYTE MOBILIZATION, PHAGOCYTOSIS AND INTRACELLULAR BACTERIAL KILLING [J].

BRAYTON, RG ;

STOKES, PE ;

SCHWARTZ, MS ;

LOURIA, DB .

NEW ENGLAND JOURNAL OF MEDICINE, 1970, 282 (03) :123-&

[5] Influence of alcohol on prognosis of pneumonia in Cook County Hospital - A statistical report [J].

Capps, JA ;

Coleman, GH .

JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1923, 80 :0750-0752

[6] MORTALITY IN RELATION TO CONSUMPTION OF ALCOHOL - 13 YEARS OBSERVATIONS ON MALE BRITISH DOCTORS [J].

DOLL, R ;

PETO, R ;

HALL, E ;

WHEATLEY, K ;

GRAY, R .

BRITISH MEDICAL JOURNAL, 1994, 309 (6959) :911-918

[7]

DUFOUR MC, 1993, ALCOHOL HEALTH RES W, V17, P265

[8] HIGH ALCOHOL INTAKE AS A RISK AND PROGNOSTIC FACTOR FOR COMMUNITY-ACQUIRED PNEUMONIA [J].

FERNANDEZSOLA, J ;

JUNQUE, A ;

ESTRUCH, R ;

MONFORTE, R ;

TORRES, A ;

URBANOMARQUEZ, A .

ARCHIVES OF INTERNAL MEDICINE, 1995, 155 (15) :1649-1654

[9] Eliciting the low-activity aldehyde dehydrogenase Asian phenotype by an antisense mechanism results in an aversion to ethanol [J].

Garver, E ;

Tu, GC ;

Cao, QN ;

Aini, M ;

Zhou, F ;

Israel, Y .

JOURNAL OF EXPERIMENTAL MEDICINE, 2001, 194 (05) :571-580

[10] MODERATE ALCOHOL INTAKE, INCREASED LEVELS OF HIGH-DENSITY-LIPOPROTEIN AND ITS SUBFRACTIONS, AND DECREASED RISK OF MYOCARDIAL-INFARCTION [J].

GAZIANO, JM ;

BURING, JE ;

BRESLOW, JL ;

GOLDHABER, SZ ;

ROSNER, B ;

VANDENBURGH, M ;

WILLETT, W ;

HENNEKENS, CH .

NEW ENGLAND JOURNAL OF MEDICINE, 1993, 329 (25) :1829-1834

← 1 2 3 4 5 6 →