The Solution Structure of (+)-Spongistatin 1 in DMSO

被引：22

作者：

Atasoylu, Onur

Furst, George

Risatti, Christina

Smith, Amos B., III ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Monell Chem Senses Ctr, Philadelphia, PA 19104 USA

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 08期

关键词：

C SPONGISTATIN 2; ALTOHYRTIN-C; ENANTIOSELECTIVE SYNTHESIS; INHIBITORS; MACROLIDE;

D O I：

10.1021/ol100417d

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

The solution structure of (+)-spongistatin 1 (1) has been determined via 1- and 2-D NMR techniques in conjunction with extensive in silico conformational analysis to comprise a mixture of 4 major rapidly interconverting conformational families.

引用

页码：1788 / 1791

页数：4

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