Acute stent thrombosis after early withdrawal of platelet glycoprotein IIb/IIIa antagonists:: Potential rebound prothrombotic effect?

被引:7
作者
Angiolillo, DJ [1 ]
Sabaté, M [1 ]
Fernández-Ortiz, A [1 ]
Macaya, C [1 ]
机构
[1] Hosp Clin Univ San Carlos, Serv Cardiol Intervencionista, Madrid, Spain
关键词
acute thrombosis; stent; platelet glycoprotein IIb/IIIa; eptifibatide; tirofiban;
D O I
10.1002/ccd.10452
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report on two cases of acute coronary stent thrombosis after early withdrawal of different competitive inhibitors of the platelet glycoprotein IIb/IIIa receptor, eptifibatide and tirofiban. Differences in pharmacokinetics between different types of glycoprotein IIb/IIIa receptor blockers and a potential rebound prothrombotic effect with the use of these antiplatelet drugs are reviewed.
引用
收藏
页码:481 / 484
页数:4
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