Application of residual dipolar coupling measurements to identify conformational changes in RNA induced by antibiotics

被引:17
作者
Lynch, SR [1 ]
Puglisi, JD [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Biol Struct, Stanford, CA 94305 USA
关键词
D O I
10.1021/ja000284n
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:7853 / 7854
页数:2
相关论文
共 23 条
[1]   Molecular symmetry as an aid to geometry determination in ligand protein complexes [J].
Al-Hashimi, HM ;
Bolon, PJ ;
Prestegard, JH .
JOURNAL OF MAGNETIC RESONANCE, 2000, 142 (01) :153-158
[2]   Refinement of the structure of protein-RNA complexes by residual dipolar coupling analysis [J].
Bayer, P ;
Varani, L ;
Varani, G .
JOURNAL OF BIOMOLECULAR NMR, 1999, 14 (02) :149-155
[3]   Residual dipolar coupling derived orientational constraints on ligand geometry in a 53 kDa protein-ligand complex [J].
Bolon, PJ ;
Al-Hashimi, HM ;
Prestegard, JH .
JOURNAL OF MOLECULAR BIOLOGY, 1999, 293 (01) :107-115
[4]   New methods of structure refinement for macromolecular structure determination by NMR [J].
Clore, GM ;
Gronenborn, AM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (11) :5891-5898
[5]  
DAVIES J, 1968, J BIOL CHEM, V243, P3312
[6]  
DAVIES J, 1965, MOL PHARMACOL, V1, P93
[7]   Domain orientation and dynamics in multidomain proteins from residual dipolar couplings [J].
Fischer, MWF ;
Losonczi, JA ;
Weaver, JL ;
Prestegard, JH .
BIOCHEMISTRY, 1999, 38 (28) :9013-9022
[8]   Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA [J].
Fourmy, D ;
Yoshizawa, S ;
Puglisi, JD .
JOURNAL OF MOLECULAR BIOLOGY, 1998, 277 (02) :333-345
[9]   Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic [J].
Fourmy, D ;
Recht, MI ;
Blanchard, SC ;
Puglisi, JD .
SCIENCE, 1996, 274 (5291) :1367-1371
[10]  
Garrett DS, 1999, NAT STRUCT BIOL, V6, P166