Computational approaches for combinatorial library design and molecular diversity analysis

被引：38

作者：

Blaney, JM ^{[1
]}

Martin, EJ ^{[1
]}

机构：

[1] Chiron Corp, Emeryville, CA 94608 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 1997年 / 1卷 / 01期

关键词：

D O I：

10.1016/S1367-5931(97)80108-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New approaches for combinatorial library design and molecular diversity analysis have been developed by extending previous work from the fields of quantitative structure-activity relationship, computational chemistry, and chemical information. Recent work has begun to address design efficiency and validation of descriptors for combinatorial library design.

引用

页码：54 / 59

页数：6

共 27 条

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