Immobilized lipase showing high catalytic activity toward enzymatic ring-opening polymerization of macrolides

被引：20

作者：

Uyama, H ^{[1
]}

Kikuchi, H ^{[1
]}

Takeya, K ^{[1
]}

Hoshi, N ^{[1
]}

Kobayashi, S ^{[1
]}

机构：

[1] TOHOKU UNIV, FAC ENGN, DEPT MOLEC CHEM & ENGN, AOBA KU, SENDAI, MIYAGI 98077, JAPAN

来源：

CHEMISTRY LETTERS | 1996年 / 02期

关键词：

D O I：

10.1246/cl.1996.107

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Immobilized Pseudomonas fluorescens lipase adsorbed on a Celite was used as new catalyst for enzymatic ring-opening polymerization of macrolides. Immobilization in the presence of a sugar or poly(ethylene glycol) greatly enhanced the catalytic activity.

引用

页码：107 / 108

页数：2

共 16 条

[1] THE INFLUENCE OF MEDIUM COMPOSITION ON THE PRODUCTION OF BACTERIAL LIPASE [J].

CUTCHINS, EC ;

DOETSCH, RN ;

PELCZAR, MJ .

JOURNAL OF BACTERIOLOGY, 1952, 63 (02) :269-272

[2] DRAMATIC ENHANCEMENT OF ENZYMATIC-ACTIVITY IN ORGANIC-SOLVENTS BY LYOPROTECTANTS [J].

DABULIS, K ;

KLIBANOV, AM .

BIOTECHNOLOGY AND BIOENGINEERING, 1993, 41 (05) :566-571

[3] APPLICATION OF POLYETHYLENE GLYCOL-MODIFIED ENZYMES IN BIOTECHNOLOGICAL PROCESSES - ORGANIC SOLVENT-SOLUBLE ENZYMES [J].

INADA, Y ;

TAKAHASHI, K ;

YOSHIMOTO, T ;

AJIMA, A ;

MATSUSHIMA, A ;

SAITO, Y .

TRENDS IN BIOTECHNOLOGY, 1986, 4 (07) :190-194

[4] REGIOSELECTIVE OXIDATION OF PHENOLS CATALYZED BY POLYPHENOL OXIDASE IN CHLOROFORM [J].

KAZANDJIAN, RZ ;

KLIBANOV, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (19) :5448-5450

[5] ASYMMETRIC TRANSFORMATIONS CATALYZED BY ENZYMES IN ORGANIC-SOLVENTS [J].

KLIBANOV, AM .

ACCOUNTS OF CHEMICAL RESEARCH, 1990, 23 (04) :114-120

[6] ENZYMATIC POLYESTERIFICATION IN ORGANIC MEDIA - ENZYME-CATALYZED SYNTHESIS OF LINEAR POLYESTERS .1. CONDENSATION POLYMERIZATION OF LINEAR HYDROXYESTERS .2. RING-OPENING POLYMERIZATION OF EPSILON-CAPROLACTONE [J].

KNANI, D ;

GUTMAN, AL ;

KOHN, DH .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 1993, 31 (05) :1221-1232

[7]

KOBAYASHI S, 1995, ADV POLYM SCI, V121, P1, DOI 10.1007/BFb0018577

[8]

MACDONALD RT, 1995, MACROMOLECULES, V28, P43

[9] A LIPID-COATED LIPASE AS A NEW CATALYST FOR TRIGLYCERIDE SYNTHESIS IN ORGANIC-SOLVENTS [J].

OKAHATA, Y ;

IJIRO, K .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1988, (20) :1392-1394

[10] ON THE IMPORTANCE OF THE SUPPORT MATERIAL FOR BIOORGANIC SYNTHESIS - INFLUENCE OF WATER PARTITION BETWEEN SOLVENT, ENZYME AND SOLID SUPPORT IN WATER-POOR REACTION MEDIA [J].

RESLOW, M ;

ADLERCREUTZ, P ;

MATTIASSON, B .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1988, 172 (03) :573-578

← 1 2 →