Chromosome dynamics: the SMC protein family

被引：76

作者：

Jessberger, R

Frei, C

Gasser, SM

机构：

[1] Basel Inst Immunol, CH-4005 Basel, Switzerland

[2] ISREC, CH-1066 Epalinges, Switzerland

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1998年 / 8卷 / 02期

关键词：

D O I：

10.1016/S0959-437X(98)80149-4

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent evidence suggests that members of the structural maintenance of chromosomes (SMC) protein family are involved in a much broader spectrum of chromosome and DNA metabolic reactions than was originally thought. Other than their role in chromosome condensation, SMC proteins are essential for sister chromatid cohesion and gene dosage compensation, and are involved in DNA recombination. This diversity of function is achieved both through the formation of different heterodimers and through their participation in higher-order protein complexes adapted to achieve specific ends. (C) Current Biology Ltd ISSN 0959-437X.

引用

页码：254 / 259

页数：6

共 32 条

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