Liver X receptor is a therapeutic target in collagen-induced arthritis

被引:38
作者
Chintalacharuvu, Subba R. [1 ]
Sandusky, George E.
Burris, Thomas P.
Nagpal, Sunil
机构
[1] Eli Lilly & Co, Indianapolis, IN 46285 USA
[2] LifeSpan Biosci, Seattle, WA USA
来源
ARTHRITIS AND RHEUMATISM | 2007年 / 56卷 / 04期
关键词
D O I
10.1002/art.22528
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1365 / 1367
页数:3
相关论文
共 8 条
[1]   Animal models of arthritis: Relevance to human disease [J].
Bendele, A ;
McComb, J ;
Gould, T ;
McAbee, T ;
Sennello, G ;
Chlipala, E ;
Guy, M .
TOXICOLOGIC PATHOLOGY, 1999, 27 (01) :134-142
[2]   An essential role for CCL3 in the development of collagen antibody-induced arthritis [J].
Chintalacharuvu, SR ;
Wang, HX ;
Giaconia, JM ;
Venkataraman, C .
IMMUNOLOGY LETTERS, 2005, 100 (02) :202-204
[3]   Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: Liver-X-receptor-specific inhibition of inflammation and primary cytokine production [J].
Fowler, AJ ;
Sheu, MY ;
Schmuth, M ;
Kao, J ;
Fluhr, JW ;
Rhein, L ;
Collins, JL ;
Willson, TM ;
Mangelsdorf, DJ ;
Elias, PM ;
Feingold, KR .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2003, 120 (02) :246-255
[4]   Reciprocal regulation of inflammation and lipid metabolism by liver X receptors [J].
Joseph, SB ;
Castrillo, A ;
Laffitte, BA ;
Mangelsdorf, DJ ;
Tontonoz, P .
NATURE MEDICINE, 2003, 9 (02) :213-219
[5]   LXRs AND FXR: The Yin and Yang of cholesterol and fat metabolism [J].
Kalaany, NY ;
Mangelsdorf, DJ .
ANNUAL REVIEW OF PHYSIOLOGY, 2006, 68 :159-191
[6]   Current and new antitumor necrosis factor agents in perspective [J].
Maini, RN .
ARTHRITIS RESEARCH & THERAPY, 2004, 6 (Suppl 2) :S1-S2
[7]   Tumour necrosis factor inhibitors [J].
Nash, PT ;
Florin, THJ .
MEDICAL JOURNAL OF AUSTRALIA, 2005, 183 (04) :205-208
[8]   Role of LXRs in control of lipogenesis [J].
Schultz, JR ;
Tu, H ;
Luk, A ;
Repa, JJ ;
Medina, JC ;
Li, LP ;
Schwendner, S ;
Wang, S ;
Thoolen, M ;
Mangelsdorf, DJ ;
Lustig, KD ;
Shan, B .
GENES & DEVELOPMENT, 2000, 14 (22) :2831-2838