Meiosis: Cell-cycle controls shuffle and deal

被引:243
作者
Marston, AL [1 ]
Amon, A [1 ]
机构
[1] MIT, Ctr Canc Res, Howard Hughes Med Inst, Cambridge, MA 02139 USA
关键词
D O I
10.1038/nrm1526
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Meiosis is the type of cell division that gives rise to eggs and sperm. Errors in the execution of this process can result in the generation of aneuploid gametes, which are associated with birth defects and infertility in humans. Here, we review recent findings on how cell-cycle controls ensure the coordination of meiotic events, with a particular focus on the segregation of chromosomes.
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收藏
页码:983 / 997
页数:15
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