Regioselective SN2 opening of α,β-ethylenic epoxides by RLi-BF3 combination

被引：18

作者：

Alexakis, A

Vrancken, E

Mangeney, P

Chemla, F

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland

[2] Univ Paris 06, Lab Chim Organoelements, UMR 7611, F-75252 Paris 05, France

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2000年 / 20期

关键词：

D O I：

10.1039/b005472k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Organolithium reagents effect a regioselective S(N)2 nucleophilic cleavage of alpha,beta-ethylenic epoxides only when BF3. Et2O is added. The reaction works with a variety of RLi reagents and with cyclic as well as acyclic epoxides.

引用

页码：3352 / 3353

页数：2

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